Department of Preventive Dentistry

Preventive dentistry is the science and technology to prevent oral diseases, to maintain normal oral functions and to promote oral health actively for an individual and a mass. The aim of preventive dentistry is to contribute to progress in QOL (quality of life) in people’s health and to lengthen the life of health (period in which people can send daily life healthily and independently) by maintaining and promoting synthetic (physical, mental and social) health through oral health. Therefore, in addition to prevent oral diseases, it is the significance of preventive dentistry to contribute for people to send high quality of living and life by maintaining and promoting oral functions such as to eat various foods with well-balanced, deliciously and tastily, and to talk pleasantly. In department of preventive dentistry, on the basis of this fundamental view, we conduct study, education and clinic.


E-mail (below@,
Atsuo Amano
Associate Professor
Masae Kuboniwa
Associate Professor
Shinichi Sekine
Assistant Professor
Hiroki Takeuchi


1. Formation of oral bacterial biofilm and its bacteria-bacteria interactions
We investigate the formation mechanism and pathogenicity of dental biofilm that causes dental caries and periodontal disease from the point of view of its bacteria-bacteria interactions by bacteriological and molecular biological techniques. This study would contribute to the development of preventive method for oral diseases.

2. Host defense system against periodontal pathogens
We investigate on the development of the new therapy with the synthesized salivary peptide or DNA vaccine, which can limit the attachment and multiplication of periodontal pathogens in oral cavity. This study may be applied to the prevention of periodontal disease.

3. Development of oral malodor measurement and prevention of halitosis
We are developing the electric nose system which imitates the mechanism of human olfaction. The absolute value evaluated by the system would be applied for deciding the diagnosis and the treatment policy of halitosis.

4. Association of lifestyle and stress factors with oral diseases
Epidemiological studies are performed on lifestyle and stress factors associated with prevalence or incidence of oral diseases such as periodontal disease and dental caries. The results are applicable in the assessment of oral health and oral health promotion.

5. Smoking as a major risk factor for periodontal disease
The potential impact of smoking on periodontal disease is investigated in the effect of tobacco smoking on the prevalence and severity of periodontal disease and in mechanisms of periodontal disease progression. This information can be used in treatment decisions and in giving advice to the patients who use tobacco products.

6. Oral health informatics
Oral health informatics is the science for preventing oral diseases and promoting oral health through optimal use of data and knowledge in dentistry and dental practices. We investigate on the development of practical data storage and retrieval system, and application of information technology to community health services.


We are in charge of lectures on Public Health and Preventive Dentistry. In the education program, we give lectures for students to master the theory and technique on oral health promotion and prevention against oral diseases, and practice them on the individual, home and community level.